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Exercise training and cytokines in breast cancer survivors

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dc.contributor.author Gómez, A. M. spa
dc.contributor.author Martínez, C. spa
dc.contributor.author Fiuza Luces, María del Carmen spa
dc.contributor.author Herrero Román, Fernando spa
dc.contributor.author Pérez Ruiz, Margarita spa
dc.contributor.author Madero López, Luis spa
dc.contributor.author Ruiz, Jonatan R. spa
dc.contributor.author Lucía Mulas, Alejandro spa
dc.contributor.author Ramírez, Manuel spa
dc.date.accessioned 2013-11-27T17:26:50Z
dc.date.available 2013-11-27T17:26:50Z
dc.date.issued 2011 spa
dc.identifier.citation Gómez, A. M., Martínez, C., Fiuza-Luces, M. C., Herrero-Román, F., Pérez-Ruiz, M., Madero-López, L., …, & Ramírez, M. (2011). Exercise training and cytokines in breast cancer survivors. International Journal of Sports Medicine, 32(6), 461-467. spa
dc.identifier.issn 14393964 spa
dc.identifier.uri http://hdl.handle.net/11268/1083
dc.description.abstract The purpose of this randomized controlled trial was to determine the effects of an 8-week (aerobic+strength) exercise training program (3 sessions/week) on the circulating cytokine levels of breast cancer survivors. We randomly allocated 16 female survivors of breast cancer (mean±SD age: 50±5 years) to an intervention or usual care (control) group (N=8 in each group). The intervention group followed an 8-week exercise program consisting of 3 sessions/week (session duration: 90 min). We measured the levels of the following cytokines before and after the intervention: beta-NGF, CTACK, eotaxin, FGF basic, G-CSF, gmCSFα, HGF, ICAM1, IFNα2, IFNγ, IL1α, IL1ß, IL1ra, IL2, IL2ra, IL3, IL4, IL6, IL7, IL8, IL9, IL10, IL12, IL13, IL15, IL16, IL17, IL18, IP10, LIF, MCS-F, MIP1α, MIP1β, MIF, MCP1, MCP3, MIG, PDGF bb, SCF, SCGFβ, SDF1α, TRAIL, TNFα, TNFβ, VCAM1, and VEGF. We only observed a significant interaction (group*time) effect for CTACK (P=0.016), with mean values remaining stable in the intervention group but increasing over time in controls. The intervention program did not induce a significant decrease in the main breast cancer-related cytokines such as IL6 and IL8. A combined (aerobic+strength) 8-week exercise training intervention did not induce major changes in the basal cytokine levels of breast cancer survivors. spa
dc.language.iso eng spa
dc.title Exercise training and cytokines in breast cancer survivors spa
dc.type article spa
dc.description.impact 2.433 JCR (2011) Q1, 14/85 Sport sciences spa
dc.identifier.doi 10.1055/s-0031-1271697 spa
dc.rights.accessRights closedAccess en
dc.subject.unesco Cáncer spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa


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