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Analysis of cerebellar changes in shape and size along development by using geometric morphometrics coordinates

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dc.contributor.author Blanco Fernández de Valderrama, María José spa
dc.contributor.author Peña-Melián, Ángel L. spa
dc.contributor.author Bastir, M. spa
dc.date.accessioned 2013-11-27T17:25:47Z
dc.date.available 2013-11-27T17:25:47Z
dc.date.issued 2008 spa
dc.identifier.citation Blanco, M. J., Peña-Melián, A., & Bastir, M. (2008). Analysis of cerebellar changes in shape and size along development by using geometric morphometrics coordinates. In Joint Meeting of the British & Spanish Developmental Biology Societies, 24th-27th September 2008. Seville, Spain. spa
dc.identifier.uri http://hdl.handle.net/11268/179
dc.description.abstract The cerebellar anlage is subject to a multifactorial process, with intrinsic and extrinsic factors, to acquire a complex adult morphological structure. The spectacular cortical development provokes dramatic changes in shape and size of the initial structure, that course with the formation of folia and fissures. The study of these transformations from a global point of view is the goal of the present study. For this approach, midsagittal sections of chick embryonic cerebella from stages HH36 to HH44 were used to obtain sets of landmarks analyzed by geometric morphometrics. This tool exploits not only the morphology per se, but the spatial relationships of anatomical structures in a quantitative and visual way. Preliminary results indicate that changes in the cerebellum are mainly observed at the transition between stages HH37-HH38, HH39-HH40 and HH40-HH41. The observed changes are summarized: 1)- the cavum ventricularis is progressively reduced to be converted into a cleft; 2)- centrifugal expansion of the folia, specially from HH40 onwards; 3)- fixation of the base of the fissures to the cerebellum core during the centrifugal expansion of the folia. spa
dc.language.iso eng spa
dc.title Analysis of cerebellar changes in shape and size along development by using geometric morphometrics coordinates spa
dc.type conferenceObject spa
dc.description.impact No data (2008) spa
dc.rights.accessRights closedAccess en
dc.subject.unesco Neurología spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa


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