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Rationale and Design of a Randomized, Double-Blind, Placebo Controlled Multicenter Trial to Study Efficacy, Security, and Long Term Effects of Intermittent Repeated Levosimendan Administration in Patients with Advanced Heart Failure: LAICA study

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dc.contributor.author García-González, Martín J. spa
dc.contributor.author Mora-Martín, Manuel de spa
dc.contributor.author López-Fernández, Silvia spa
dc.contributor.author López-Díaz, Javier spa
dc.contributor.author Martínez Sellés Oliveria Soares, Manuel spa
dc.contributor.author Romero-García, José spa
dc.contributor.author Cordero, Marco spa
dc.contributor.author Lara-Padrón, Antonio spa
dc.contributor.author Marrero-Rodríguez, Francisco spa
dc.contributor.author García-Saiz, María del Mar spa
dc.date.accessioned 2014-03-18T10:09:18Z
dc.date.available 2014-03-18T10:09:18Z
dc.date.issued 2013 spa
dc.identifier.citation García-González, M. J., Mora-Martín, M., López-Fernández, S., López-Díaz, J., Martínez-Sellés, M., Romero-García, J., ..., & García-Sáiz, M. M. (2013).Rationale and design of a randomized, double-blind, placebo controlled multicenter trial to study efficacy, security, and long term effects of intermittent repeated levosimendan administration in patients with advanced heart failure: LAICA study. Cardiovascular Drugs and Therapy, 27(6), 573-579. spa
dc.identifier.issn 09203206 spa
dc.identifier.uri http://hdl.handle.net/11268/2184
dc.description.abstract Advanced heart failure (HF) is associated with high morbidity and mortality; it represents a major burden for the health system. Episodes of acute decompensation requiring frequent and prolonged hospitalizations account for most HF-related expenditure. Inotropic drugs are frequently used during hospitalization, but rarely in out-patients. The LAICA clinical trial aims to evaluate the effectiveness and safety of monthly levosimendan infusion in patients with advanced HF to reduce the incidence of hospital admissions for acute HF decompensation. spa
dc.language.iso eng spa
dc.title Rationale and Design of a Randomized, Double-Blind, Placebo Controlled Multicenter Trial to Study Efficacy, Security, and Long Term Effects of Intermittent Repeated Levosimendan Administration in Patients with Advanced Heart Failure: LAICA study spa
dc.type article spa
dc.description.impact 2.952 JCR (2013) Q2, 45/125 Cardiac & cardiovascular systems, 79/254 Pharmacology & pharmacy spa
dc.identifier.doi 10.1007/s10557-013-6476-7 spa
dc.rights.accessRights closedAccess en
dc.subject.unesco Enfermedad cardiovascular spa
dc.subject.unesco Tratamiento médico spa
dc.peerreviewed Si spa


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