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Follow-up in healthy schoolchildren and in adolescents with DOWN syndrome: psycho-environmental and genetic determinants of physical activity and its impact on fitness, cardiovascular diseases, inflammatory biomarkers and mental health; the UP&DOWN Study.

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dc.contributor.author Castro-Piñero, José
dc.contributor.author Carbonell-Baeza, Ana
dc.contributor.author Martínez-Gómez, David
dc.contributor.author Gómez Martínez, Sonia
dc.contributor.author Cabañas Sánchez, Verónica
dc.contributor.author Santiago Dorrego, Catalina
dc.contributor.author Veses, A. M.
dc.contributor.author Bandrés Moya, Fernando
dc.contributor.author González-Galo, A.
dc.contributor.author Gómez Gallego, Félix
dc.contributor.author Veiga, Óscar Luis
dc.contributor.author Ruiz, Jonatan R.
dc.contributor.author Marcos, Ascensión
dc.date.accessioned 2014-05-08T13:07:21Z
dc.date.available 2014-05-08T13:07:21Z
dc.date.issued 2014 spa
dc.identifier.citation Castro-Piñero, J., Carbonell-Baeza, A., Martínez-Gómez, D., Gómez-Martínez, S., Cabanas-Sánchez, V., Santiago-Dorrego, C., ..., & Marcos, A. (2014). Follow-up in healthy schoolchildren and in adolescents with DOWN syndrome: psycho-environmental and genetic determinants of physical activity and its impact on fitness, cardiovascular diseases, inflammatory biomarkers and mental health, the UP&DOWN study. BMC Public Health, 14, 400. spa
dc.identifier.issn 14712458 spa
dc.identifier.uri http://hdl.handle.net/11268/2947
dc.description.abstract BACKGROUND: An objective diagnosis of sedentary behaviour as well as of the physical activity and fitness levels in youth and to better understand how lifestyle is associated with cardiovascular disease risk factors and other phenotypes is of clinical and public health interest, and might be informative for developing intervention studies focused on the promotion of physical activity in these population. The aim of this methodological paper is to describe the design and assessment in the UP&DOWN study. METHODS: The UP&DOWN study is a multi-center follow-up design where 2225 Spanish primary and secondary schoolchildren from Cadiz and Madrid, respectively, as well as 110 Spanish adolescents with Down syndrome from Madrid and Toledo were recruited to be assessed. Nine main measurement categories are assessed: i) socio-demographic and early determinants; ii) environmental determinants; iii) physical activity and sedentary behaviour; iv) health-related fitness; v) blood pressure and resting heart rate; vi) mental health; vii) dietary patterns; viii) blood samples; and ix) genetic analysis. During the 3-yr follow-up study, socio-demographic and early determinants, and genetic analysis are only assessed in the first year. Blood sampling is assessed in the first year and the third year (2nd follow-up), and all the other measurements are assessed every year. DISCUSSION: The findings of the UP&DOWN study may help the Health Information Systems and policy makers to identify the target population for primary prevention and health promotion policies, and to develop and test preventive strategies. Moreover, these data will allow following the trends at population level, as well as to modify/adapt/create new evidence-based physical activity guidelines at national level. The findings will also serve as a scientific platform for interventional studies spa
dc.description.sponsorship Evaluación de la interacción entre genética y actividad física en el estado físico y la salud en escolares y adolescentes con Síndrome de Down: estudio de seguimiento a tres años Plan Nacional de I+D+i. Ministerio de Ciencia e Innovación (Ref. DEP2010-21662-C04-02). spa
dc.language.iso eng spa
dc.rights Atribución-NoComercial-SinDerivadas 3.0 España *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/es/ *
dc.title Follow-up in healthy schoolchildren and in adolescents with DOWN syndrome: psycho-environmental and genetic determinants of physical activity and its impact on fitness, cardiovascular diseases, inflammatory biomarkers and mental health; the UP&DOWN Study. spa
dc.type article spa
dc.description.impact 2.264 JCR (2014) Q2, 53/162 Public, environmental & occupational health spa
dc.identifier.doi 10.1186/1471-2458-14-400 spa
dc.rights.accessRights openAccess spa
dc.subject.uem Deportes y recreación spa
dc.subject.uem Educación física - enseñanza spa
dc.subject.unesco Educación física spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa


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