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Valve surgery in active infective endocarditis: a simple score to predict in-hospital prognosis

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dc.contributor.author Martínez Sellés Oliveria Soares, Manuel
dc.contributor.author Muñoz, Patricia
dc.contributor.author Arnáiz, Ana María
dc.contributor.author Moreno, Mar
dc.contributor.author Gálvez-Acebal, Juan
dc.contributor.author Rodríguez-Roda, Jorge R.
dc.contributor.author Alarcón González, Arístides de
dc.contributor.author García-Cabrera, Emilio
dc.contributor.author Fariñas, María Carmen
dc.contributor.author Miró, J. M.
dc.contributor.author Montejo, Miguel L.
dc.contributor.author Moreno, Alfonso Soto
dc.contributor.author Ruiz-Morales, Josefa
dc.contributor.author Goenaga, Miguel Ángel
dc.contributor.author Bouza, Emilio
dc.date.accessioned 2015-06-17T14:50:23Z
dc.date.available 2015-06-17T14:50:23Z
dc.date.issued 2014
dc.identifier.citation Martínez-Sellés, M., Muñoz, P., Arnáiz, A., Moreno, M., Gálvez, J., Rodríguez-Roda, J., ..., & Bouza, E. (2014). Valve surgery in active infective endocarditis: a simple score to predict in-hospital prognosis. International Journal of Cardiology, 175(1), 133-137. spa
dc.identifier.issn 01675273
dc.identifier.uri http://hdl.handle.net/11268/4016
dc.description.abstract Aims Surgery for infective endocarditis (IE) is associated with high mortality. Our objectives were to describe the experience with surgical treatment for IE in Spain, and to identify predictors of in-hospital mortality. Methods Prospective cohort of 1000 consecutive patients with IE. Data were collected in 26 Spanish hospitals. Results Surgery was performed in 437 patients (43.7%). Patients treated with surgery were younger and predominantly male. They presented fewer comorbid conditions and more often had negative blood cultures and heart failure. In-hospital mortality after surgery was lower than in the medical therapy group (24.3 vs 30.7%, p = 0.02). In patients treated with surgery, endocarditis involved a native valve in 267 patients (61.1%), a prosthetic valve in 122 (27.9%), and a pacemaker lead with no clear further valve involvement in 48 (11.0%). The most common aetiologies were Staphylococcus (186, 42.6%), Streptococcus (97, 22.2%), and Enterococcus (49, 11.2%). The main indications for surgery were heart failure and severe valve regurgitation. A risk score for in-hospital mortality was developed using 7 prognostic variables with a similar predictive value (OR between 1.7 and 2.3): PALSUSE: prosthetic valve, age ≥ 70, large intracardiac destruction, Staphylococcus spp, urgent surgery, sex [female], EuroSCORE ≥ 10. In-hospital mortality ranged from 0% in patients with a PALSUSE score of 0 to 45.4% in patients with PALSUSE score > 3. Conclusions The prognosis of IE surgery is highly variable. The PALSUSE score could help to identify patients with higher in-hospital mortality. spa
dc.language.iso eng spa
dc.subject.other Endocarditis infecciosa spa
dc.subject.other Estratificación de riesgos spa
dc.title Valve surgery in active infective endocarditis: a simple score to predict in-hospital prognosis spa
dc.type article spa
dc.description.impact 4.036 JCR (2014) Q1, 29/123 Cardiac and cardiovascular systems spa
dc.identifier.doi 10.1016/j.ijcard.2014.04.266
dc.rights.accessRights closedAccess spa
dc.subject.uem Cardiología spa
dc.subject.unesco Sistema cardiovascular spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa


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