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ARDS: A Clinical Syndrome or a Pathological Entity?

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dc.contributor.author Cardinal Fernández, Pablo
dc.contributor.author Ballén Barragán, A.
dc.contributor.author Lorente Balanza, José Ángel
dc.date.accessioned 2015-07-16T17:00:40Z
dc.date.available 2015-07-16T17:00:40Z
dc.date.issued 2014
dc.identifier.citation Cardinal-Fernández, P., Barragán, A. B., & Lorente, J. A. (2014). ARDS: A Clinical Syndrome or a Pathological Entity?. In Annual Update in Intensive Care and Emergency Medicine 2014 (pp. 219-229). Springer International Publishing. spa
dc.identifier.isbn 9783319037455
dc.identifier.isbn 9783319037462
dc.identifier.issn 21915709
dc.identifier.uri http://hdl.handle.net/11268/4205
dc.description.abstract Despite substantial advances in the understanding of the pathogenesis of the acute respiratory distress syndrome (ARDS), no specific pharmacologic treatment has been shown to affect outcome. This failure has been attributed in part to a lack of a reliable definition for ARDS. Indeed, how the target population is defined for a clinical trial affects the results and their generalizability. Studies including patients with a low probability of responding to the treatment under study (because they are unlikely to have the diagnosis or because of other reasons) are likely to yield false-negative results. Thus a reliable definition of ARDS is essential for research (clinical trials, epidemiologic studies, and studies on pathogenesis) and for clinical practice (to reliably make a diagnosis of ARDS and provide appropriate treatment). In this context several relevant questions arise: What are the different diagnostic criteria for the definition of ARDS? What are the diagnostic test characteristics of these different criteria considering diffuse alveolar damage (DAD) as the histological reference for the diagnosis of ARDS? Does the clinical phenotype of ARDS correlate with one or with more histological entities? Is DAD the sole histological manifestation of ARDS? spa
dc.language.iso eng spa
dc.publisher Springer International Publishing spa
dc.relation.ispartofseries Annual Update in Intensive Care and Emergency Medicine: 2014 spa
dc.subject.other Síndrome de dificultad respiratoria aguda spa
dc.title ARDS: A Clinical Syndrome or a Pathological Entity? spa
dc.type bookPart spa
dc.description.impact No data (2014) spa
dc.identifier.doi 10.1007/978-3-319-03746-2_17
dc.rights.accessRights closedAccess spa
dc.subject.uem Aparato respiratorio - Enfermedades spa
dc.subject.unesco Patología spa
dc.subject.unesco Aparato respiratorio spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa


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