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Review of the efficacy and safety of fesoterodine for treating overactive bladder and urgency urinary incontinence in elderly patients

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dc.contributor.author Wagg, Adrian
dc.contributor.author Oelke, Matthias
dc.contributor.author Angulo Cuesta, Javier
dc.contributor.author Scholfield, David
dc.contributor.author Arumí Torredemer, Daniel
dc.date.accessioned 2015-07-25T13:31:42Z
dc.date.available 2015-07-25T13:31:42Z
dc.date.issued 2015
dc.identifier.citation Wagg, A., Oelke, M., Angulo, J. C., Scholfield, D., & Arumi, D. (2015). Review of the efficacy and safety of fesoterodine for treating overactive bladder and urgency urinary incontinence in elderly patients. Drugs & Aging, 32(2), 103-125. spa
dc.identifier.issn 1170229X
dc.identifier.issn 11791969
dc.identifier.uri http://hdl.handle.net/11268/4259
dc.description.abstract Overactive bladder (OAB) is a common condition, with prevalence rates increasing with advancing age. Symptoms of OAB, including urgency urinary incontinence (UUI), are associated with various co-morbidities in elderly individuals (e.g., falls and fractures, functional impairment, and depression). The current mainstay of pharmacological therapy for OAB is antimuscarinic agents. Until recently, few studies had specifically evaluated the efficacy and safety of antimuscarinics in the treatment of OAB symptoms in elderly patients. This review summarises available evidence from the medical literature on the efficacy and safety of fesoterodine in elderly patients with OAB symptoms, including UUI. The data from unique placebo-controlled fesoterodine trials of elderly and vulnerable elderly patients, together with age-stratified data from post hoc analyses of fesoterodine trials, demonstrate that treatment with fesoterodine 4 or 8 mg results in statistically and clinically significant improvements in OAB symptoms and patient-reported outcomes in many elderly patients. spa
dc.language.iso eng spa
dc.subject.other Fesoterodina spa
dc.subject.other Incontinencia urinaria spa
dc.title Review of the efficacy and safety of fesoterodine for treating overactive bladder and urgency urinary incontinence in elderly patients spa
dc.type article spa
dc.description.impact 2.610 JCR (2015) Q2, 22/49 Geriatrics & Gerontology, 98/253 Pharmacology & Pharmacy spa
dc.identifier.doi 10.1007/s40266-014-0237-6
dc.rights.accessRights openAccess spa
dc.subject.uem Urología spa
dc.subject.unesco Cirugía spa
dc.description.filiation UEM spa
dc.relation.publisherversion http://ezproxy.universidadeuropea.es/login?url=http:/ /dx.doi.org/10.1007/s40266-014-0237-6 spa
dc.peerreviewed Si spa


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