The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity?

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dc.contributor.author Fuku, Noriyuki
dc.contributor.author Pareja Galeano, Helios
dc.contributor.author Zempo, Hirofumi
dc.contributor.author Alis, Rafael
dc.contributor.author Arai, Yasumichi
dc.contributor.author Lucía Mulas, Alejandro
dc.contributor.author Hirose, Nobuyoshi
dc.date.accessioned 2015-10-15T07:21:57Z
dc.date.available 2015-10-15T07:21:57Z
dc.date.issued 2015
dc.identifier.citation Fuku, N., Pareja‐Galeano, H., Zempo, H., Alis, R., Arai, Y., Lucía, A., & Hirose, N. (2015). The mitochondrial‐derived peptide MOTS‐c: a player in exceptional longevity?. Aging cell. spa
dc.identifier.issn 14749718
dc.identifier.issn 14749726
dc.identifier.uri http://hdl.handle.net/11268/4414
dc.description.abstract Mitochondrial-derived peptides (MDP) are encoded by functional short open reading frames in the mitochondrial DNA (mtDNA). These include humanin, and the recently discovered mitochondrial open reading frame of the 12S rRNA-c (MOTS-c). Although more research is needed, we suggest that the m.1382A>C polymorphism located in the MOTS-c encoding mtDNA, which is specific for the Northeast Asian population, may be among the putative biological mechanisms explaining the high longevity of Japanese people. spa
dc.language.iso eng spa
dc.rights Atribución-NoComercial-SinDerivadas 3.0 España *
dc.rights Attribution 4.0 International *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/es/ *
dc.rights.uri http://creativecommons.org/licenses/by/4.0/ *
dc.subject.other Aging spa
dc.subject.other Centenarians spa
dc.subject.other Longevity gene spa
dc.subject.other Longevity regulation spa
dc.subject.other Mitochondria spa
dc.subject.other Mitochondrial DNA spa
dc.subject.other Mitochondrial DNA abnormalities spa
dc.subject.other Molecular biology of aging spa
dc.title The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity? spa
dc.type article spa
dc.description.impact 5.760 JCR (2015) Q1, 36/187 Cell biology, 3/49 Geriatrics & gerontology spa
dc.identifier.doi 10.1111/acel.12389
dc.rights.accessRights openAccess spa
dc.subject.uem Genética humana spa
dc.subject.uem Biología spa
dc.subject.unesco Gen spa
dc.subject.unesco Genética humana spa
dc.subject.unesco Biología molecular spa
dc.subject.unesco Biología humana spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa

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