Are mitochondrial haplogroups associated with elite athletic status? A study on a Spanish cohort

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dc.contributor.author Nogales-Gadea, Gisela spa
dc.contributor.author Pinós, Tomás spa
dc.contributor.author Ruiz, Jonatan R. spa
dc.contributor.author Femia Marzo, Pedro spa
dc.contributor.author Fiuza Luces, María del Carmen spa
dc.contributor.author López-Gallardo, Ester spa
dc.contributor.author Ruiz-Pesini, Eduardo spa
dc.contributor.author Martín, Miguel Ángel spa
dc.contributor.author Arenas, Joaquín spa
dc.contributor.author Morán, María spa
dc.contributor.author Andreu, Antoni L. spa
dc.contributor.author Lucía Mulas, Alejandro spa
dc.date.accessioned 2013-11-27T17:26:09Z
dc.date.available 2013-11-27T17:26:09Z
dc.date.issued 2011 spa
dc.identifier.citation Nogales-Gadea, G., Pinós, T., Ruiz, J. R., Femia-Marzo, P. F., Fiuza-Luces, M. C., López-Gallardo, E., …, & Lucía-Mulas, A. (2011). Are mitochondrial haplogroups associated with elite athletic status? A study on a Spanish cohort. Mitochondrion, 11(6), 905-908. spa
dc.identifier.uri http://hdl.handle.net/11268/491
dc.description.abstract There is increasing evidence regarding the association between mitochondrial DNA (mtDNA) and aerobic capacity; however, whether mtDNA haplogroups are associated with the status of being an elite endurance athlete is more controversial. We compared the frequency distribution of mtDNA haplogroups among the following groups of Spanish (Caucasian) men: 102 elite endurance athletes (professional road cyclists, endurance runners), 51 elite power athletes (jumpers, throwers and sprinters), and 478 non-athletic controls. We observed a significant difference between endurance athletes and controls (Fisher exact test=17.89, P=0.015; Bonferroni's significant threshold=0.017), yet not between power athletes and controls (Fisher exact test=47.99, P=0.381) or between endurance and power athletes (Fisher exact test=5.53, P=0.597). We observed that the V haplogroup was overrepresented in endurance athletes (15.7%) compared with controls (7.5%) (odds ratio: 2.284; 95% confidence interval: 1.237, 4.322). In conclusion, our findings overall support the idea that mtDNA variations could be among the numerous contributors to the status of being an elite endurance athlete, whereas no association was found with elite power athletic status. spa
dc.language.iso eng spa
dc.title Are mitochondrial haplogroups associated with elite athletic status? A study on a Spanish cohort spa
dc.type article spa
dc.description.impact 3.615 JCR (2011) Q2, 78/181 Cell biology, 45/158 Genetics & heredity spa
dc.identifier.doi 10.1016/j.mito.2011.08.002 spa
dc.rights.accessRights closedAccess en
dc.subject.unesco Genética humana spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa

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