A Paradox: α-Klotho Levels and Smoking Intensity

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dc.contributor.author Verde Rello, Zoraida
dc.contributor.author Gonzalez-Moro, Jose Miguel
dc.contributor.author Chicharro García, Luis Miguel
dc.contributor.author Reinoso Barbero, Luis
dc.contributor.author Bandrés Moya, Fernando
dc.contributor.author Gómez Gallego, Félix
dc.contributor.author Santiago Dorrego, Catalina
dc.date.accessioned 2016-10-30T19:11:28Z
dc.date.available 2016-10-30T19:11:28Z
dc.date.issued 2017
dc.identifier.citation Verde, Z., González-Moro, J. M. R., Chicharro, L. M., Reinoso-Barbero, L., Bandrés, F., Gómez-Gallego, F., & Santiago, C. (2017). A Paradox: α-Klotho Levels and Smoking Intensity. Lung, 195(1), 53-57. DOI: 10.1007/s00408-016-9944-6 spa
dc.identifier.issn 0341-2040
dc.identifier.uri http://hdl.handle.net/11268/5937
dc.description.abstract Reports regarding smoking differences in aklotho expression have provided conflicting results. In the current study we focused on the influence of smoking intensity to serum levels of the aging molecule a-klotho in healthy smokers. 40 middle aged healthy smokers without airway obstruction or restriction were selected for the analysis. Serum levels of soluble a-klotho were significantly higher in heavy smokers (P\0.001). These results are in agreement with the possibility that a-klotho acts as anti-inflammatory molecule and strengthen the hypothesis that an increase of serum levels of a-klotho might be a compensatory response to smoking stress in healthy population. spa
dc.description.sponsorship NEUMOMADRID (2015) spa
dc.language.iso eng spa
dc.title A Paradox: α-Klotho Levels and Smoking Intensity spa
dc.type article spa
dc.description.impact 2.101 JCR (2017) Q3, 40/59 Respiratory System spa
dc.identifier.doi 10.1007/s00408-016-9944-6
dc.rights.accessRights closedAccess spa
dc.subject.uem Médicina spa
dc.subject.unesco Ciencias médicas spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa

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