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Chagas disease screening among HIV-positive Latin American immigrants: an emerging problem

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dc.contributor.author Llenas-García, Jara spa
dc.contributor.author Hernando Jeréz, María Asunción spa
dc.contributor.author Fiorante, Silvana spa
dc.contributor.author Maseda, Diego spa
dc.contributor.author Matarranz, Mariano spa
dc.contributor.author Salto, Efrén spa
dc.contributor.author Rubio, Rafael spa
dc.contributor.author Pulido, Federico spa
dc.date.accessioned 2013-11-27T17:26:19Z
dc.date.available 2013-11-27T17:26:19Z
dc.date.issued 2012 spa
dc.identifier.citation Llenas-García, J., Hernando-Jerez, A., Fiorante, S., Maseda, D., Matarranz, M., Salto, E., ..., & Pulido, F. (2012). Chagas disease screening among HIV-positive latin american immigrants: an emerging problem. European Journal of Clinical Microbiology & Infectious Diseases, 31(8), 1991-1997. spa
dc.identifier.uri http://hdl.handle.net/11268/630
dc.description.abstract Chagas disease (CD) is an emergent disease in Europe that can behave as an opportunistic infection in HIV positive patients. The objective of this study was to evaluate the implementation of a CD screening programme in an HIV unit. An immunochromatography (ICT) of Trypanosoma cruzi was performed as a screening tool in HIV-positive patients born in CD endemic countries. ELISA and IFAT were used to confirm the diagnosis. A total of 155 patients, 116 males and 38 females, were included. Mean age was 36.9 years (± 8.4) and mean length of stay in Spain at the screening was 7.1 years (± 4.7). T. cruzi ICT was positive in four cases (2.6%), being confirmed (by ELISA and IFAT) in three of those (1.9%). Factors associated with confirmed positive T.cruzi serology were: Bolivia origin (p=0.016), Bolivia or Argentina origin (p=0.002), Southern Cone origin (p=0.015), rural origin (p=0.023), previously living in an adobe-made (p=0.001) or thatch-roofed house (p<0.0001), having a previous CD test (p=0.015), previous knowledge about CD (p=0.019), about vector (p=0.009) or recorded seeing vectors at home (p=0.012). Units dealing with HIV patients from endemic areas of American trypanosomiasis should implement CD screening protocols. Interviews of patients coming from endemic areas should include CD epidemiological questions. spa
dc.language.iso eng spa
dc.title Chagas disease screening among HIV-positive Latin American immigrants: an emerging problem spa
dc.type article spa
dc.description.impact 3.024 JCR (2012) Q2, 25/70 Infectious disseases, 43/116 Microbiology spa
dc.identifier.doi 10.1007/s10096-011-1531-4 spa
dc.rights.accessRights closedAccess en
dc.subject.unesco Enfermedad tropical spa
dc.peerreviewed Si spa


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