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Does the polygenic profile determine the potential for becoming a world-class athlete? Insights from the sport of rowing

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dc.contributor.author Santiago Dorrego, Catalina spa
dc.contributor.author Ruiz, Jonatan R. spa
dc.contributor.author Muniesa Ferrero, Carlos Alberto spa
dc.contributor.author González-Freire, Marta spa
dc.contributor.author Gómez Gallego, Félix spa
dc.contributor.author Lucía Mulas, Alejandro spa
dc.date.accessioned 2013-11-27T17:26:22Z
dc.date.available 2013-11-27T17:26:22Z
dc.date.issued 2010 spa
dc.identifier.citation Santiago-Dorrego, C., Ruiz, J. R., Muniesa-Ferrero, C. A., González‐Freire, M., Gómez‐Gallego, F., & Lucía-Mulas, A. (2010). Does the polygenic profile determine the potential for becoming a world‐class athlete? Insights from the sport of rowing. Scandinavian Journal of Medicine & Science in Sports, 20(1), e188-e194. spa
dc.identifier.issn 09057188 spa
dc.identifier.uri http://hdl.handle.net/11268/664
dc.description.abstract We determined whether the polygenic profile computed with seven candidate polymorphisms (i.e., ACE, ACTN3, AMPD1, CKMM, HFE, GDF-8 and PPARGC1A) for endurance performance is different in 39 world-class and 15 national-class Spanish (Caucasian) lightweight rowers. The second purpose was to examine the impact of possessing a "preferable" polygenic profile on the sport success in terms of the number of medals won in World and National Championships. Finally, we also compared the polygenic profile of world- and national-class Spanish rowers with that of the general Spanish population. The polygenic profile did not differ between groups of rowers. We did not observe an association between having a preferable polygenic profile and medals won in World and National Championships. Finally, we observed that rowers tend to have a more "favorable" polygenic profile than the general Spanish population. These findings argue against the idea that genetic endowment differentiates athletic champions from elite, yet less accomplished athletes. In contrast, we cannot discard the fact that, overall, elite athletes are endowed with a more "favorable" polygenic profile than the general population. spa
dc.language.iso eng spa
dc.subject.other Multifactorial Inheritance* spa
dc.subject.other Polymorphism, Genetic* spa
dc.subject.other Sports/*Physiology spa
dc.subject.other European Continental Ancestry Group/Genetics spa
dc.subject.other Genotype spa
dc.subject.other Humans spa
dc.subject.other Male spa
dc.subject.other Physical Endurance/Physiology spa
dc.subject.other Spain spa
dc.title Does the polygenic profile determine the potential for becoming a world-class athlete? Insights from the sport of rowing spa
dc.type article spa
dc.description.impact 2.794 JCR (2010) Q1, 8/80 Sport sciences spa
dc.identifier.doi 10.1111/j.1600-0838.2009.00943.x spa
dc.rights.accessRights openAccess en
dc.subject.unesco Genética humana spa
dc.subject.unesco Fisiología humana spa
dc.subject.unesco Atleta spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa


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