Emerging technologies for salivaomics in cancer detection

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dc.contributor.author Kaczor-Urbanowicz, Karolina
dc.contributor.author Martín Carreras-Presas, Carmen
dc.contributor.author Kaczor, T.
dc.contributor.author Tu, Michael
dc.contributor.author Wei, F.
dc.contributor.author Garcia-Godoy, Franklin
dc.contributor.author Wong, David T. W.
dc.date.accessioned 2017-12-11T22:16:07Z
dc.date.available 2017-12-11T22:16:07Z
dc.date.issued 2017
dc.identifier.citation Kaczor‐Urbanowicz, K. E., Martín Carreras‐Presas, C., Kaczor, T., Tu, M., Wei, F., Garcia‐Godoy, F., & Wong, D. T. (2017). Emerging technologies for salivaomics in cancer detection. Journal of Cellular and Molecular Medicine, 21(4), 640-647. DOI: 10.1111/jcmm.13007 spa
dc.identifier.issn 1582-4934
dc.identifier.uri http://hdl.handle.net/11268/6854
dc.description.abstract Salivary diagnostics has great potential to be used in the early detection and prevention of many cancerous diseases. If implemented with rigour and efficiency, it can result in improving patient survival times and achieving earlier diagnosis of disease. Recently, extraordinary efforts have been taken to develop non-invasive technologies that can be applied without complicated and expensive procedures. Saliva is a biofluid that has demonstrated excellent properties and can be used as a diagnostic fluid, since many of the biomarkers suggested for cancers can also be found in whole saliva, apart from blood or other body fluids. The currently accepted gold standard methods for biomarker development include chromatography, mass spectometry, gel electrophoresis, microarrays and polymerase chain reaction-based quantification. However, salivary diagnostics is a flourishing field with the rapid development of novel technologies associated with point-of-care diagnostics, RNA sequencing, electrochemical detection and liquid biopsy. Those technologies will help introduce population-based screening programs, thus enabling early detection, prognosis assessment and disease monitoring. The purpose of this review is to give a comprehensive update on the emerging diagnostic technologies and tools for the early detection of cancerous diseases based on saliva. spa
dc.description.sponsorship Sin financiación spa
dc.language.iso eng spa
dc.rights Attribution-NonCommercial-NoDerivatives 4.0 Internacional *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/ *
dc.title Emerging technologies for salivaomics in cancer detection spa
dc.type article spa
dc.description.impact 4.302 JCR (2017) Q1, 25/133 Medicine, Research and Experimental; Q2, 67/190 Cell Biology spa
dc.identifier.doi 10.1111/jcmm.13007
dc.rights.accessRights openAccess spa
dc.subject.uem Odontología spa
dc.subject.uem Cáncer spa
dc.subject.unesco Odontología spa
dc.subject.unesco Cáncer spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa

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Attribution-NonCommercial-NoDerivatives 4.0 Internacional Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional