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Predictors of high Killip class after ST segment elevation myocardial infarction in the era of primary reperfusion

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dc.contributor.author Vicent, Lourdes
dc.contributor.author Velásquez Rodríguez, Jesús
dc.contributor.author Valero Masa, María Jesús
dc.contributor.author Díez Delhoyo, Felipe
dc.contributor.author González Saldivar, Hugo
dc.contributor.author Bruña, Vanesa
dc.contributor.author Devesa Cordero, Carolina
dc.contributor.author Juárez Fernández, Miriam
dc.contributor.author Sousa Casasnovas, Iago
dc.contributor.author Fernández-Avilés, Francisco
dc.contributor.author Martínez Sellés Oliveria Soares, Manuel
dc.date.accessioned 2017-12-11T22:25:47Z
dc.date.available 2017-12-11T22:25:47Z
dc.date.issued 2017
dc.identifier.citation Vicent, L., Velásquez-Rodríguez, J., Valero-Masa, M. J., Díez-Delhoyo, F., González-Saldívar, H., Bruña, V., ... & Martínez-Sellés, M. (2017). Predictors of high Killip class after ST segment elevation myocardial infarction in the era of primary reperfusion. International Journal of Cardiology, 248, 46-50. spa
dc.identifier.issn 0167-5273
dc.identifier.issn 1874-1754
dc.identifier.uri http://hdl.handle.net/11268/6855
dc.description.abstract Background/Introduction: Outcome after ST segment elevation myocardial infarction (STEMI), has improved but patients with high Killip class still have a poor prognosis, and those ≥ II need a closer monitoring in a specialized cardiac care unit. Purpose: We aimed to determine the predictors of Killip class in a group of patients admitted for acute STEMI. Methods: Non-interventional registry in a Cardiac Intensive Care Unit. Patients were consecutively included from January 2010 to April 2015, and multivariate analysis was performed to determine independent predictors of high Killip Class. Results: We included 1111 patients, mean age was 64.0 ± 14.0 years and 258 (23.2%) were female. Primary percutaneous coronary intervention was performed in 991 (89.2%), and 120 (10.8%) only received thrombolysis as acute reperfusion therapy. A total of 230 (20.7%) were in class II or higher. The independent predictors of Killip ≥ II were (odds ratio [95% confidence interval]): older age (2.1 [1.4–3.0]), female sex (1.6 [1.1–2.2]), diabetes (1.4 [1.0–2.1]), prior heart failure (3.2 [1.4–7.2]), chronic kidney disease (2.0 [1.1–3.6]), anaemia (3.0 [2.0–4.5]), multivessel disease (1.6 [1.1–2.2]), anterior location (2.4 [1.8–3.4]), time of evolution > 2 h (1.6 [1.1–2.4]), and TIMI flow-grade < 3 (1.8 [1.2–2.7]). In-hospital mortality increased with Killip class (I 1.5%, II 3.7%, III 16.7%, IV 36.7%). Conclusion: In patients with STEMI Killip class can be predicted with variables available when primary percutaneous coronary intervention is performed and is strongly associated with in-hospital prognosis. spa
dc.description.sponsorship SIN FINANCIACIÓN spa
dc.language.iso eng spa
dc.title Predictors of high Killip class after ST segment elevation myocardial infarction in the era of primary reperfusion spa
dc.type article spa
dc.description.impact 4.034 JCR (2017) Q2, 41/128 Cardiac and Cardiovascular Systems spa
dc.identifier.doi 10.1016/j.ijcard.2017.07.038
dc.rights.accessRights closedAccess spa
dc.subject.uem Cardiología spa
dc.subject.uem Mortalidad spa
dc.subject.unesco Enfermedad cardiovascular spa
dc.subject.unesco Mortalidad spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa


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