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Relation of quality of anticoagulation control with different management systems among patients with atrial fibrillation: Data from FANTASIIA Registry

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dc.contributor.author Roldán, Inmaculada
dc.contributor.author Esteve Pastor, María Asunción
dc.contributor.author Anguita, Manuel
dc.contributor.author Muñiz, Javier
dc.contributor.author Camacho Siles, J.
dc.contributor.author Quesada, M. A.
dc.contributor.author Ruiz Ortiz, Martín
dc.contributor.author Marín, Francisco
dc.contributor.author Martínez Sellés Oliveria Soares, Manuel
dc.contributor.author Badimón, Lina
dc.contributor.author Et al.
dc.date.accessioned 2018-05-14T08:00:12Z
dc.date.available 2018-05-14T08:00:12Z
dc.date.issued 2018
dc.identifier.citation Roldán Rabadán, I., Esteve‐Pastor, M. A., Anguita‐Sánchez, M., Muñiz, J., Camacho Siles, J., Quesada, M. A., ... & Badimón, L. (2018). Relation of quality of anticoagulation control with different management systems among patients with atrial fibrillation: Data from FANTASIIA Registry. European Journal of Clinical Investigation, 48(5), e12910. DOI: 10.1111/eci.12910 spa
dc.identifier.issn 0014-2972
dc.identifier.issn 1365-2362
dc.identifier.uri http://hdl.handle.net/11268/7267
dc.description.abstract Background: Anticoagulation control in patients with atrial fibrillation (AF) has a multidisciplinary approach although is usually managed by general practitioners (GP) or haematologists. The aim of our study was to assess the quality of anticoagulation control with vitamin K antagonists (VKAs) in relation to the responsible specialist in a "real-world" AF population. Methods: We consecutively enrolled VKA anticoagulated patients included in the FANTASIIA Registry from 2013 to 2015. We analysed demographical, clinical characteristics and the quality of anticoagulation control according to the specialist responsible (ie GPs or haematologists). Results: Data on 1584 patients were included (42.5% females, mean age 74.0 ± 9.4 years): 977 (61.7%) patients were controlled by GPs and 607 (38.3%) by haematologists. Patients managed by GPs had higher previous heart disease (53.2% vs 43.3%, P < .001), heart failure (32.9% vs 26.5%, P < .008) and dilated cardiomyopathy (15.2% vs 8.7%, P < .001) with better renal function (69.3 ± 24.7 vs 63.1 ± 21.4 mL/min, P < .001) compared to patients managed by haematologists. There was no difference between groups in the type of AF, CHA2 DS2 -VASc or HAS-BLED scores, but patients with electrical cardioversion were more prevalent in GP group. The overall mean time in therapeutic range (TTR) assessed by Rosendaal method was 61.5 ± 24.9%; 52.6% of patients had TTR<65% and 60% of patients had TTR<70%. TTR was significantly lower in patients controlled by haematologists than by GPs (63 ± 24.4 vs 59.2 ± 25.6, P < .005). Conclusions: About 60% of AF patients anticoagulated with VKAs had poor anticoagulation control (ie TTR<70%), and their management was only slightly better than when it is managed by general practitioners. spa
dc.description.sponsorship SIN FINANCIACIÓN spa
dc.language.iso eng spa
dc.title Relation of quality of anticoagulation control with different management systems among patients with atrial fibrillation: Data from FANTASIIA Registry spa
dc.type article spa
dc.description.impact 2.784 JCR (2018) Q1, 37/160 Medicine, General & Internal; Q2, 67/136 Medicine, Research & Experimental spa
dc.identifier.doi 10.1111/eci.12910
dc.rights.accessRights closedAccess spa
dc.subject.uem Anticoagulantes spa
dc.subject.uem Fibrilación auricular spa
dc.subject.uem Hematología spa
dc.subject.unesco Sistema cardiovascular spa
dc.subject.unesco Tratamiento médico spa
dc.description.filiation UEM spa
dc.relation.publisherversion http://ezproxy.universidadeuropea.es/login?url=http:/ /dx.doi.org/10.1111/eci.12910 spa
dc.peerreviewed Si spa


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