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Rationale and design of the FELICITAR registry (Frailty Evaluation After List Inclusion, Characteristics and Influence on Transplantation and Results)

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dc.contributor.author Ayesta, Ana
dc.contributor.author Vidán, María Teresa
dc.contributor.author Valero Masa, María Jesús
dc.contributor.author Segovia Cubero, Javier
dc.contributor.author García Cosío, María Dolores
dc.contributor.author Martínez Sellés Oliveria Soares, Manuel
dc.date.accessioned 2018-06-08T08:58:51Z
dc.date.available 2018-06-08T08:58:51Z
dc.date.issued 2018
dc.identifier.citation Ayesta, A., Vidán-Astiz, M. T., Valero-Masa, M. J., Segovia, J., García-Cosío, M. D., & Martínez‐Sellés, M. (2018). Rationale and design of the FELICITAR registry (Frailty Evaluation After List Inclusion, Characteristics and Influence on Transplantation and Results). Clinical Cardiology, 41(3), 293-299. DOI: 10.1002/clc.22871 spa
dc.identifier.issn 0160-9289
dc.identifier.issn 1932-8737
dc.identifier.uri http://hdl.handle.net/11268/7292
dc.description.abstract Frailty reflects a state of decreased physiological reserve and vulnerability to stressors. Its prevalence among patients with cardiovascular disease is as high as 60%. Frailty is associated with a poor prognosis for patients with heart failure, increasingly frequent hospitalization, and death. The recent published listing criteria for heart transplantation of the International Society for Heart and Lung Transplantation recommend assessing frailty (class IIb recommendation, level of evidence C). However, this recommendation is not based on prospective studies, and frailty scores have only been validated in patients age > 65 years. The aim of the FELICITAR registry (Frailty Evaluation After List Inclusion, Characteristics and Influence on Transplantation and Results) is to assess the impact of frailty on prognosis before and after heart transplantation. A series of 100 patients from 3 Spanish centers will be included as soon as they are added to the national heart transplantation waiting list. Frailty will be evaluated again every 3 months until heart transplantation and at 3, 6, and 12 months thereafter. Depression, cognitive assessment, and quality of life also will be analyzed. The 2 primary endpoints are all‐cause mortality and prevalence of frailty assessed using the Fried frailty index. Results from this study may show that frailty is frequent in patients with advanced heart failure listed for heart transplantation and is associated with a poor prognosis both before and after surgery. The findings may contribute to a better understanding of the characteristics of the optimal candidate for heart transplantation. spa
dc.description.sponsorship Grant 2017 of the Spanish Society of Cardiology, Heart Failure and Heart Transplantation Section spa
dc.description.sponsorship Cátedra ASISA‐Universidad Europea de Madrid 2017/UEM31 spa
dc.language.iso eng spa
dc.title Rationale and design of the FELICITAR registry (Frailty Evaluation After List Inclusion, Characteristics and Influence on Transplantation and Results) spa
dc.type article spa
dc.description.impact 2.455 JCR (2018) Q2, 67/136 Cardiology & Cardiovascular Medicine spa
dc.identifier.doi 10.1002/clc.22871
dc.rights.accessRights openAccess spa
dc.subject.uem Trasplante de órganos spa
dc.subject.uem Corazón spa
dc.subject.uem Pronóstico médico spa
dc.subject.unesco Enfermedad cardiovascular spa
dc.subject.unesco Trasplante de órganos spa
dc.description.filiation UEM spa
dc.relation.publisherversion http://dx.doi.org/10.1002/clc.22871 spa
dc.peerreviewed Si spa


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