Salivaomics in oral cancer

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dc.contributor.author Aro, Katri
dc.contributor.author Kaczor-Urbanowicz, Karolina
dc.contributor.author Martín Carreras-Presas, Carmen
dc.date.accessioned 2019-01-08T16:25:27Z
dc.date.available 2019-01-08T16:25:27Z
dc.date.issued 2019
dc.identifier.citation Aro, K., Kaczor-Urbanowicz, K., & Martín Carreras-Presas, C. (2019). Salivaomics in oral cancer. Current Opinion in Otolaryngology & Head and Neck Surgery, 27(2), 91-97. http://doi.org/10.1097/MOO.0000000000000502 spa
dc.identifier.issn 1068-9508
dc.identifier.uri http://hdl.handle.net/11268/7718
dc.description.abstract The goal of cancer screening is to detect tumor at an early stage, and early cancer detection is the hallmark of successful treatment. In addition to traditional tissue biopsy-based diagnostics, more reliable, inexpensive, and noninvasive methods are required for early diagnosis of cancer. In this review, we highlight some of the recent advancements in the field of salivary diagnostics in oral cancer. RECENT FINDINGS: 'Salivaomics' is a broad collection of technologies used to explore different types of molecules contained in saliva. Although many protein and mRNA salivary biomarkers have been identified that can detect oral squamous cell carcinoma (OSCC), none have so far been validated for current clinical use. As the heterogeneity in carcinogenesis and multifactorial cause for OSCC, the most reliable results are gathered with the use of multiple biomarker candidates to improve accuracy and sensitivity of the test used. This further requires sensitive technology to detect salivary biomarkers in low quantities. SUMMARY: Large scale studies that incorporate proteomic, transcriptomic, and additional 'omics,' need to be initiated to bring technology to clinical point-of-care applications. spa
dc.description.sponsorship Sin financiación spa
dc.language.iso eng spa
dc.title Salivaomics in oral cancer spa
dc.type article spa
dc.description.impact 1.607 JCR (2019) Q3, 23/42 Otorhinolaringology spa
dc.description.impact 0.702 SJR (2019) Q2, 127/451 Surgery, 38/111 Otorhinolaryngology, 907/2754 Medicine (miscellaneous) spa
dc.description.impact No data IDR 2019 spa
dc.identifier.doi 10.1097/MOO.0000000000000502
dc.rights.accessRights closedAccess spa
dc.subject.uem Odontología spa
dc.subject.uem Cáncer spa
dc.subject.unesco Odontología spa
dc.subject.unesco Cáncer spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa

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