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Signs of subclinical myocarditis in a cohort of professional football players: a magnetic resonance imaging and genetic test study

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dc.contributor.author González Caballero, Eva spa
dc.contributor.author Pizarro, Gonzalo spa
dc.contributor.author Fuertes Suárez, Beatriz spa
dc.contributor.author Bayona, S. spa
dc.contributor.author Machado, J. C. spa
dc.contributor.author Luna, A. spa
dc.contributor.author Caro, P. spa
dc.contributor.author Sánchez-Quintana, Damián spa
dc.contributor.author Cabrera Rodríguez, José Ángel spa
dc.date.accessioned 2013-11-27T17:26:31Z
dc.date.available 2013-11-27T17:26:31Z
dc.date.issued 2010 spa
dc.identifier.citation González-Caballero, E., Pizarro, G., Fuertes-Suárez, B., Bayona, S., Machado, J. C., Luna, A., ... & Cabrera-Rodríguez, J. A. (2010). Signs of subclinical myocarditis in a cohort of professional football players: a magnetic resonance imaging and genetic test study. European Heart Journal, 31(s-1), 387. spa
dc.identifier.issn 0195668X spa
dc.identifier.uri http://hdl.handle.net/11268/797
dc.description.abstract Athletes possess greater relative risk of sudden death due to cardiovascular causes, where autopsies reveal myocardial fibrosis. Although hypertrophic cardiomyopathy (HCM) has been consistently reported to be the single most common cause of cardiovascular death, myocarditis can also be an important entity in this population. A cohort of 25 healthy male professional football (soccer) players (mean age 31±4 years old), with a high dynamic (isotonic) component training history was studied. A complete cardiovascular evaluation including anamnesis, physical examination, 12-lead ECG, magnetic resonance imaging (MRI) with delayed enhancement sequences and genetic analysis (MYH7, MYBPC3, ACT1, PKP2, DSP, DSG2, TAZ/G4.5, ZASP/LDB3 and DTNA genes) was performed. Seven out of 25 athelets (28%) had an abnormal MRI study. Four of them (16%) had signs compatible with myo-pericarditis (three had subepicardial fibrosis and one had pericardial effusion). In five (20%) players, LV apical hyper trabeculation (two with diagnostic criteria of LV non-compaction) was found. EKG repolarization abnormalities were detected in four (16%) athletes. No mutations were detected in the cardiomyopathy genetic tests. In conclusion, in a professional football players population, magnetic resonance imaging can detect signs of myocarditis, which could be a singular entity affecting this high dynamic component sport. spa
dc.language.iso eng spa
dc.subject.other Cardiovascular System & Cardiology spa
dc.title Signs of subclinical myocarditis in a cohort of professional football players: a magnetic resonance imaging and genetic test study spa
dc.type article spa
dc.description.impact 10.052 JCR (2010) Q1, 3/114 Cardiac & cardiovascular systems spa
dc.rights.accessRights closedAccess en
dc.subject.unesco Enfermedad cardiovascular spa
dc.peerreviewed Si spa


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