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Octogenarian women with acute coronary syndrome present frailty and readmissions more frequently than men

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dc.contributor.author Vicent, Lourdes
dc.contributor.author Ariza Solé, Albert
dc.contributor.author Alegre, Oriol
dc.contributor.author Sanchís, Juan
dc.contributor.author López-Palop, Ramón
dc.contributor.author Formiga, Francesc
dc.contributor.author González Salvado, Violeta
dc.contributor.author Bueno, Héctor
dc.contributor.author Vidán, María Teresa
dc.contributor.author Martínez Sellés Oliveria Soares, Manuel
dc.contributor.author Et al.
dc.date.accessioned 2019-06-17T07:25:51Z
dc.date.available 2019-06-17T07:25:51Z
dc.date.issued 2019
dc.identifier.citation Vicent, L., Ariza-Solé, A., Alegre, O., Sanchís, J., López-Palop, R., Formiga, F., ... & Martínez-Sellés, M. (2019). Octogenarian women with acute coronary syndrome present frailty and readmissions more frequently than men. European Heart Journal: Acute Cardiovascular Care, 8(3), 252-263. https://doi.org/10.1177/2048872618798226 spa
dc.identifier.issn 2048-8726
dc.identifier.issn 2048-8734
dc.identifier.uri http://hdl.handle.net/11268/8047
dc.description.abstract Background: A worse prognosis has been reported among women with acute coronary syndrome compared to men. Our aim was to address the role of frailty and sex in the management and prognosis of elderly patients with non-ST-segment elevation acute coronary syndrome. Methods: A prospective registry in 44 Spanish hospitals including patients aged 80 years and older with non-ST-segment elevation acute coronary syndrome. Frailty assessment was performed using the FRAIL scale. Results: Of a total of 535 patients, 207 (38.7%) were women. Mean age was 84.8±4.0 years, similar in men and women. A prior history of coronary artery disease was more common in men (146, 44.9%) than in women (46, 22.2%), P<0.001. Frailty was less frequent in men (65, 20.2%) than in women (77, 37.8%), P<0.001. Female sex was an independent predictor of death/hospitalisation (hazard ratio (HR) 1.7, 95% confidence interval (CI) 1.1–2.4) and of hospitalisation at 6 months (HR 1.6, 95% CI 1.04–2.4). In men, compared to non-frail patients, both a prefrail status (HR 3.47, 95% CI 1.22–9.89) and frailty (HR 3.19, 95% CI 1.08–9.43) were independently associated with higher mortality. In women only frailty was independently associated with higher mortality (HR 5.68, 95% CI 1.91–16.18, compared to prefrailty or robustness). Frailty was associated with readmissions in men (HR 3.34, 95% CI 1.79–6.22) but not in women. Conclusions: In octogenarians with acute coronary syndrome female sex was independently associated with death/hospitalisation at 6 months. Frailty was more common in women and was a predictor of poor prognosis. In men prefrailty also predicted a poor prognosis. spa
dc.description.sponsorship Sin financiación spa
dc.language.iso eng spa
dc.title Octogenarian women with acute coronary syndrome present frailty and readmissions more frequently than men spa
dc.type article spa
dc.description.impact 3.813 JCR (2019) Q2, 47/138 Cardiac & Cardiovascular Systems spa
dc.description.impact 1.630 SJR (2019) Q1, 46/362 Cardiology and Cardiovascular Medicine, 9/91 Critical Care and Intensive Care Medicine, 208/2754 Medicine (miscellaneous) spa
dc.description.impact No data IDR 2019 spa
dc.identifier.doi 10.1177/2048872618798226
dc.rights.accessRights closedAccess spa
dc.subject.uem Síndrome coronario agudo spa
dc.subject.uem Geriatría spa
dc.subject.unesco Enfermedad cardiovascular spa
dc.subject.unesco Gerontología spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa


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