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Determinants of long-term survival in patients hospitalized for heart failure

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dc.contributor.author Martínez Sellés Oliveria Soares, Manuel spa
dc.contributor.author Martínez, Esther spa
dc.contributor.author Cortés, Marcelino spa
dc.contributor.author Prieto Castillejo, Raquel spa
dc.contributor.author Gallego Parra, Laura spa
dc.contributor.author Fernández-Avilés, Francisco spa
dc.date.accessioned 2013-11-27T17:26:31Z
dc.date.available 2013-11-27T17:26:31Z
dc.date.issued 2010 spa
dc.identifier.citation Martínez-Sellés, M., Martínez, E., Cortés, M., Prieto, R., Gallego, L., & Fernández-Avilés, F. (2010). Determinants of long-term survival in patients hospitalized for heart failure. Journal of Cardiovascular Medicine, 11(3), 164-169. spa
dc.identifier.issn 15582035 spa
dc.identifier.uri http://hdl.handle.net/11268/813
dc.description.abstract Background and Objectives: Methods: Results: Conclusion: Current models used to stratify patients with heart failure are complex, difficult to use, and limited by short follow-up and patient selection. Our aim was to determine predictors of long-term survival in patients hospitalized for heart failure and to develop a simple mortality risk score to estimate long-term mortality.We prospectively followed up, during 10 years after hospitalization, 701 patients with confirmed heart failure from the HOLA (Heart failure: Observation of Local Admissions) registry.Mean age was 72.4 +/- 11.7 years; 45% were men. During follow-up, 465 patients died and 5 underwent heart transplantation. A total of 231 patients (33%) were alive and transplant-free at the end of follow-up (5.2 +/- 4.2 years). Median survival was 3.2 years. Multivariate analysis showed that six variables (age, previous renal disease, previous stroke, chronic obstructive pulmonary disease, left ventricular ejection fraction and aortic stenosis) were independent predictors of shorter survival time. By dichotomizing these variables, we obtained six factors with similar predictive values (hazard ratio between 1.5 and 2.0). A risk score for mortality was developed using these predictors by assigning 1 point to each and adding the total for each patient. Median survival for patients with 0, 1, 2, and 3 or more points were 6.5, 5.5, 3.3, and 1.7 years, respectively. One-year mortality rates were 15, 20, 28, and 49%, respectively.The prognosis of patients hospitalized with heart failure is highly variable. A simple risk score, based on six variables readily obtainable on admission can effectively stratify patients according to their predicted mortality. spa
dc.language.iso eng spa
dc.subject.other Health Status Indicators* spa
dc.subject.other Heart Failure/*Mortality spa
dc.subject.other Hospitalization/*Statistics & Numerical Data spa
dc.subject.other Survivors/*Statistics & Numerical Data spa
dc.subject.other Aortic Valve Stenosis/Mortality spa
dc.subject.other Female spa
dc.subject.other Follow-Up Studies spa
dc.subject.other Heart Failure/Physiopathology spa
dc.subject.other Heart Failure/Ultrasonography spa
dc.subject.other Humans spa
dc.subject.other Kaplan-Meier Estimate spa
dc.subject.other Kidney Diseases/Mortality spa
dc.subject.other Male spa
dc.subject.other Middle Aged spa
dc.subject.other Prognosis spa
dc.subject.other Proportional Hazards Models spa
dc.subject.other Prospective Studies spa
dc.subject.other Pulmonary Disease, Chronic Obstructive/Mortality spa
dc.subject.other Registries spa
dc.subject.other Risk Assessment spa
dc.subject.other Risk Factors spa
dc.subject.other Stroke/Mortality spa
dc.subject.other Stroke Volume spa
dc.subject.other Time Factors spa
dc.subject.other Ventricular Function, Left spa
dc.title Determinants of long-term survival in patients hospitalized for heart failure spa
dc.type article spa
dc.description.impact 0.786 JCR (2010) Q4, 97/114 Cardiac & cardiovascular systems spa
dc.identifier.doi 10.2459/JCM.0b013e328332ea96 spa
dc.rights.accessRights closedAccess en
dc.subject.unesco Enfermedad cardiovascular spa
dc.subject.unesco Análisis cuantitativo spa
dc.peerreviewed Si spa


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