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Risk factors of pericardial effusion in native valve infective endocarditis and its influence on outcome: A multicenter prospective cohort study

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dc.contributor.author Regueiro, Ander
dc.contributor.author Falces, Carles
dc.contributor.author Pericás, Juan M.
dc.contributor.author Muñoz, Patricia
dc.contributor.author Martínez Sellés Oliveria Soares, Manuel
dc.contributor.author Valerio Minero, Maricela
dc.contributor.author Sousa Regueiro, Dolores
dc.contributor.author Castelo, Laura
dc.contributor.author Alarcón González, Arístides de
dc.contributor.author Grupo de Apoyo al Manejo de la Endocarditis Infecciosa en España (GAMES)
dc.contributor.author Et al.
dc.date.accessioned 2020-03-26T18:26:22Z
dc.date.available 2020-03-26T18:26:22Z
dc.date.issued 2018
dc.identifier.citation Regueiro, A., Falces, C., Pericás, J. M., Muñoz, P., Martínez-Sellés, M., Valerio, M., Sousa Regueiro, D., Castelo, L., Alarcón González, A. de, Cobo Belaustegui, M., Goenaga, M. A., Hidalgo-Tenorio, C., Martínez-Marcos, F. J., Gainzarain Arana, J. C., Miro, J. M., & Grupo de Apoyo al Manejo de la Endocarditis Infecciosa en España (GAMES). (2018). Risk factors of pericardial effusion in native valve infective endocarditis and its influence on outcome: A multicenter prospective cohort study. International Journal of Cardiology, 273, 193–198. https://doi.org/10.1016/j.ijcard.2018.08.010 spa
dc.identifier.issn 0167-5273
dc.identifier.issn 1874-1754
dc.identifier.uri http://hdl.handle.net/11268/8858
dc.description.abstract Background Pericardial effusion is a frequent finding in the setting of infective endocarditis. Limited data exists on clinical characteristics and outcomes in this group of patients. We aimed to determine the associated factors, clinical characteristics, and outcomes of patients who had pericardial effusion and native valve infective endocarditis. Methods and results A total of 1205 episodes of infective endocarditis from 25 Spanish centers between June 2007 and March 2013 within the Spanish Collaboration on Endocarditis (GAMES) registry were included. Echocardiogram at admission, clinical and microbiological variables, and one-year follow-up were analyzed. Pericardial effusion was observed in 7.8% (94/1205 episodes) of episodes of infective endocarditis, most of them being mild or moderate (93.6%). The presence of pericardial effusion was associated with a higher risk of heart failure during admission (OR 1.9; CI 95% 1.2–3.0). Patients with pericardial effusion had a higher rate of surgery (53.2% vs. 41.1%; p = 0.02); however, this association was no longer significant after adjusting for possible confounders (OR 1.4; CI 95% 0.9–2.2; p = 0.10). The presence of pericardial effusion was not associated with a higher in-hospital or one-year mortality (33.0% vs. 25.2%; p = 0.10 and 40.2% vs. 37.3%; p = 0.60 respectively). Conclusions The prevalence of pericardial effusion in patients with infective endocarditis was lower than previously reported. The presence of pericardial effusion is associated with the development of heart failure during hospitalization making it a warning sign, possibly reflecting indirectly a mechanical complication, which, however, if treated surgically in a timely manner does not change the final outcome of patients. spa
dc.description.sponsorship Sin financiación spa
dc.language.iso eng spa
dc.title Risk factors of pericardial effusion in native valve infective endocarditis and its influence on outcome: A multicenter prospective cohort study spa
dc.type article spa
dc.description.impact 3.471 JCR (2018) Q2, 48/136 Cardiac & Cardiovascular Systems spa
dc.description.impact 0.990 SJR (2018) Q2, 91/365 Cardiology and Cardiovascular Medicine spa
dc.description.impact No data IDR 2018 spa
dc.identifier.doi 10.1016/j.ijcard.2018.08.010
dc.rights.accessRights closedAccess spa
dc.subject.uem Enfermos cardíacos spa
dc.subject.uem Tratamiento médico spa
dc.subject.uem Ecocardiografía spa
dc.subject.unesco Enfermedad cardiovascular spa
dc.subject.unesco Tratamiento médico spa
dc.subject.unesco Tecnología médica spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa


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