Unhealthy Stem Cells: When Health Conditions Upset Stem Cell Properties

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dc.contributor.author Martín Pérez, Laura
dc.contributor.author Lucas Moreno, Beatriz de
dc.contributor.author González Gálvez, Beatriz
dc.date.accessioned 2021-02-10T17:11:56Z
dc.date.available 2021-02-10T17:11:56Z
dc.date.issued 2018
dc.identifier.citation Pérez, L. M., Lucas, B., & González Gálvez, B. (2018). Unhealthy Stem Cells: When Health Conditions Upset Stem Cell Properties. Cellular Physiology and Biochemistry, 46(5), 1999–2016. https://doi.org/10.1159/000489440 spa
dc.identifier.issn 1421-9778
dc.identifier.issn 1015-8987
dc.identifier.uri http://hdl.handle.net/11268/9832
dc.description.abstract The stem cell field has grown very rapidly during the last decade, offering the promise of innovative therapies to treat disease. Different stem cell populations have been isolated from various human adult tissues, mainly from bone marrow and adipose tissue, but many other body tissues harbor a stem cell population. Adult tissue stem cells are invariably found in discrete microenvironments termed niches, where they play key roles in tissue homeostasis by enabling lifelong optimization of organ form and function. Some diseases are known to strike at the stem cell population, through alterations in their specific microenvironments, making them non-viable. Furthermore, it has been shown that a transformed stem cell population could prompt the development of certain cancers. This review focuses on the potential negative aspects of a range of diseases on the activity of stem cells and how their potential use in cell therapies may be affected. spa
dc.description.sponsorship Sin financiación spa
dc.language.iso eng spa
dc.rights Attribution-NonCommercial-NoDerivatives 4.0 Internacional *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/ *
dc.subject.other Células madre spa
dc.subject.other Terapéutica spa
dc.subject.other Tratamiento basado en trasplante de células y tejidos spa
dc.title Unhealthy Stem Cells: When Health Conditions Upset Stem Cell Properties spa
dc.type article spa
dc.description.impact No data JCR 2018 spa
dc.description.impact 1.292 SJR (2018) Q2, 51/188 Physiology spa
dc.description.impact No data IDR 2018 spa
dc.identifier.doi 10.1159/000489440
dc.rights.accessRights openAccess spa
dc.subject.unesco Biología celular spa
dc.subject.unesco Fisiología humana spa
dc.subject.unesco Tratamiento médico spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa

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Attribution-NonCommercial-NoDerivatives 4.0 Internacional Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional