Neurohormonal Modulation as a Therapeutic Target in Pulmonary Hypertension

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dc.contributor.author García Lunar, Inés
dc.contributor.author Pereda, Daniel
dc.contributor.author Ibáñez, Borja
dc.contributor.author García Álvarez, Ana
dc.date.accessioned 2021-02-15T11:32:10Z
dc.date.available 2021-02-15T11:32:10Z
dc.date.issued 2020
dc.identifier.citation García-Lunar, I., Pereda, D., Ibáñez, B., & García-Álvarez, A. (2020). Neurohormonal Modulation as a Therapeutic Target in Pulmonary Hypertension. Cells, 9(11), 2521. https://doi.org/10.3390/cells9112521 spa
dc.identifier.issn 2073-4409
dc.identifier.uri http://hdl.handle.net/11268/9853
dc.description.abstract The autonomic nervous system (ANS) and renin-angiotensin-aldosterone system (RAAS) are involved in many cardiovascular disorders, including pulmonary hypertension (PH). The current review focuses on the role of the ANS and RAAS activation in PH and updated evidence of potential therapies targeting both systems in this condition, particularly in Groups 1 and 2. State of the art knowledge in preclinical and clinical use of pharmacologic drugs (beta-blockers, beta-three adrenoceptor agonists, or renin-angiotensin-aldosterone signaling drugs) and invasive procedures, such as pulmonary artery denervation, is provided. spa
dc.description.sponsorship Fondo Europeo de Desarrollo Regional (FEDER) spa
dc.description.sponsorship Instituto de SaludCarlos III - Fondo de Investigación Sanitaria (PI17/00995) e Intensificación (AES2019) spa
dc.description.sponsorship Ministerio de Ciencia, Innovación y Universidades spa
dc.description.sponsorship Severo Ochoa Center of Excellence (SEV-2015-0505) spa
dc.language.iso eng spa
dc.rights Attribution-NonCommercial-NoDerivatives 4.0 Internacional *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/ *
dc.subject.other Hipertensión pulmonar spa
dc.subject.other Sistema nervioso autónomo spa
dc.subject.other Sistema renina-angiotensina spa
dc.title Neurohormonal Modulation as a Therapeutic Target in Pulmonary Hypertension spa
dc.type article spa
dc.description.impact 4.034 JCR (2019) Q2, 70/195 Cell Biology spa
dc.description.impact No data SJR 2019 spa
dc.description.impact No data IDR 2019 spa
dc.identifier.doi 10.3390/cells9112521
dc.rights.accessRights openAccess spa
dc.subject.unesco Aparato respiratorio spa
dc.subject.unesco Enfermedad cardiovascular spa
dc.description.filiation UEM spa
dc.peerreviewed Si spa

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Attribution-NonCommercial-NoDerivatives 4.0 Internacional Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional