TY - JOUR A1 - Vicent, Lourdes AU - Guerra, José AU - Vázquez García, Rafael AU - González Juanatey, José Ramón AU - Martínez Dolz, Luis AU - Segovia Cubero, Javier AU - Pascual Figal, Domingo AU - Bover Freire, Ramón AU - Worner, Fernando AU - Martínez Sellés Oliveria Soares, Manuel AU - Et al. T1 - Ischemic Etiology and Prognosis in Men and Women with Acute Heart Failure Y1 - 2021 SN - 2077-0383 UR - http://hdl.handle.net/11268/10279 AB - Coronary heart disease is common in heart failure (HF). Our aim was to determine the impact of ischemic etiology on prognosis among men and women with HF. This study is a prospective national multicenter registry. The primary endpoint was 12-month mortality. Patients with HF and ischemic heart disease were stratified according to sex. A total of 1830 patients were enrolled of which 756 (41.3%) were women. Ischemic etiology was more common in men (446 (41.6%)) than in women (167 (22.2%)). Among patients with ischemic HF, diabetes was more frequent in women than in men. Ischemic etiology was not associated with higher mortality risk, and this was true for women (Hazard Ratio [HR] 1.51, 95% Confidence Interval [CI] 0.98–2.32; p = 0.61) and men (HR 1.14, 95% CI 0.81–1.61; p = 0.46), p-value for interaction: 0.067. Mortality/readmission risk in ischemic HF increased in men with previous readmissions (HR 1.15, 95% CI 1.02–1.29; p = 0.022), chronic obstructive pulmonary disease (HR1.20, 95% CI 1.02–1.41; p = 0.026) and in women with diabetes (HR 2.23, 95% CI 1.05–4.47; p = 0.035). Ischemic etiology was not associated with mortality in HF patients. In ischemic HF, the variables associated with a poor prognosis were diabetes in women and previous readmissions and chronic obstructive pulmonary disease in men. KW - Insuficiencia cardiaca KW - Enfermedad cardiovascular KW - Distribución por sexo KW - Mortalidad LA - eng ER -