TY - JOUR 
A1 - Arroyo Úcar, Eduardo
AU - Moreno, Raúl
AU - García, Eulogio
AU - Teles, Rui
AU - Rumoroso, José Ramón
AU - Carvalho, Henrique Cyrne
AU - Goicolea, Francisco Javier
AU - Moreu, José
AU - Sabaté, Manel
AU - Mainar, Vicente
AU - Patricio, Lino
AU - Valdés, Mariano
AU - Fernández Vázquez, Felipe
AU - Sánchez-Recalde, Ángel
AU - Galeote, Guillermo
AU - Jiménez-Valero, Santiago
AU - Almeida, Manuel
AU - López de Sa, Esteban
AU - Calvo, Luis
AU - Plaza Pérez, Ignacio
AU - López-Sendón, José Luis
AU - Rodríguez Martín, José Luis
T1 - Drug-eluting stent thrombosis in the treatment of chronic total coronary occlusions: Incidence, presentation and related factors. Data from the CIBELES trial

Y1 - 2015
SN - 08702551
UR - http://hdl.handle.net/11268/3889
AB - Introduction and Objectives: The aim of this study was to analyze the incidence of drug-eluting stent thrombosis (sirolimus or everolimus) in patients with chronic total coronary occlusions (CTO) and to determine its clinical implications and related factors. Methods: Data from the 12-month follow-up of the 207 patients included in the CIBELES trial with CTO were analyzed. Results: Stent thrombosis occurred in three patients, two definite and one probable (overall thrombosis rate: 1.4%). However, there were no cases of death or Q-wave myocardial infarction. In univariate analysis, patients with a higher incidence of stent thrombosis were those in whom the target vessel was the left anterior descending, who had single-vessel disease, were assigned to treatment with sirolimus-eluting stents, and those with smaller minimum luminal diameter immediately after the procedure. In multivariate analysis, the only independent predictor of stent thrombosis was minimal luminal diameter immediately after the procedure. Conclusions: The rate of drug-eluting stent thrombosis in patients with CTO is relatively low (1.4%). The only independent predictor of stent thrombosis in this context was minimal luminal diameter after the procedure and the clinical presentation was in all cases relatively benign.
KW - Stent
KW - Thrombosis
KW - Everolimus
KW - Sirolimus
KW - Chronic total coronary occlusion
KW - Stents
KW - Enfermedad coronaria - Cirugía
KW - Trombosis
KW - Sistema cardiovascular
LA - eng
ER -