TY - JOUR 
A1 - Santodomingo Rubido, Jacinto
AU - Villa Collar, César
AU - Gilmartin, Bernard
AU - Gutiérrez Ortega, Ángel Ramón
T1 - Orthokeratology vs. spectacles: Adverse events and discontinuations
Y1 - 2012
SN - 10405488
UR - http://hdl.handle.net/11268/652
AB - PURPOSE: To assess the relative clinical success of orthokeratology contact lenses (OK) and distance single-vision spectacles (SV) in children in terms of incidences of adverse events and discontinuations over a 2-year period.
METHODS: Sixty-one subjects 6 to 12 years of age with myopia of - 0.75 to - 4.00DS and astigmatism ≤1.00DC were prospectively allocated OK or SV correction. Subjects were followed at 6-month intervals and advised to report to the clinic immediately should adverse events occur. Adverse events were categorized into serious, significant, and non-significant. Discontinuation was defined as cessation of lens wear for the remainder of the study.
RESULTS: Thirty-one children were corrected with OK and 30 with SV. A higher incidence of adverse events was found with OK compared with SV (p < 0.001). Nine OK subjects experienced 16 adverse events (7 significant and 9 non-significant). No adverse events were found in the SV group. Most adverse events were found between 6 and 12 months of lens wear, with 11 solely attributable to OK wear. Significantly more discontinuations were found with SV in comparison with OK (p < 0.05).
CONCLUSIONS: The relatively low incidence of adverse events and discontinuations with OK is conducive for the correction of myopia in children with OK contact lenses.
KW - Myopia Control
KW - Orthokeratology
KW - Adverse Events
KW - Discontinuations
KW - Drop Out
KW - Spectacles
KW - Rates
KW - Overnight Orthokeratology
KW - Berkeley Orthokeratology
KW - Contact-Lenses
KW - Hong-Kong
KW - Children
KW - Myopia
KW - Safety
KW - Eyes
KW - Ophthalmology
KW - Oftalmología
LA - eng
ER -